Experimental Phage Therapies in Companion Animals with A Historical Review

Author(s):

Ewelina Pyzik, Renata Urban-Chmiel* and Radosław P. Radzki Pages 1-13 (13)

Abstract:

Aim: The aim of review was to comprehensively characterize the antimicrobial efficacy of bacteriophages in eliminating pathogens occurring in companion animals, as an alternative to antibiotics for controlling infections that pose potential threats to the health and life of people and to the environment.

Methods: The review contains detailed information on the characteristics and classification of bacteriophages and an analysis of their life cycle. The dominant element is a detailed analysis of the experimental use of bacteriophages in combating infections caused by various microorganisms in companion animals with regard to their potential use in therapy.

Results: It seems that in the near future phage therapies will provide an alternative to antibiotics in the treatment of diseases caused by multi-drug resistant bacteria in people and animals. Conclusions: The effectiveness of phages therapies depends on many factors and the properties of the bacteriophages themselves, which requires comprehensive knowledge of them.

Keywords:

bacteriophages, therapy, companion animals, bacterial viruses, antibacterial therapy, antibiotic resistance

Affiliation:

Department of Veterinary Prevention and Avian Diseases, University of Life Sciences in Lublin, Institute of Biological Bases of Animal Diseases. SubDepartment of Veterinary Prevention and Avian Diseases, University of Life Sciences in Lublin, Akademicka 12 , Department of Animal Physiology, University of Life Sciences in Lublin, Akademicka 12

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